TY - GEN T1 - Analysis of clinical and diagnostic findings during exposures in chemical nanotechnology T3 - Overview of activities in nanotechnologies : NANODATA ; Metz, Wednesday 24 & Thursday 25 November 2010. - Metz, 2010 A1 - Mittmann-Frank,Michaela A1 - Berger,Hendrik A1 - Kraegeloh,Annette A1 - Pföhler,Claudia A1 - Bücker,Arno A1 - Wilkens,Heinrike A1 - Buchter,Axel Y1 - 2011/05/02 N2 - The rapid development of nanotechnology - the key technology of the 21th century - demands a consideration of risks and assessment of health effects during exposures to nanomaterials. Due to their high surface to volume ratio, nanoscaled materials exhibit exceptional physical and chemical properties when compared to larger particles of the same composition. Therefore toxicological informations of the bulk material should be carefully applied to nano particles. One of the most relevant uptake pathways is the inhalation of nanoscaled particles. Effects on the respiratory tract like inflammation, oxidative stress and pulmonary fibrosis, adverse effects on the cardiovascular and central nervous system are considered. In addition, nanotubes with their structure similar to asbestos-fibres may have a carcinogenic potential. Taking into consideration the various possible working mechanism of nanomaterials, an extensive diagnostic program was designed and offered to a collective of employees in chemical nanotechnology. KW - Nanotechnologie KW - Nanopartikel KW - Zirkonium KW - Arbeitsmedizin KW - Diagnostik CY - Saarbrücken PB - Universitäts- und Landesbibliothek AD - Postfach 151141, 66041 Saarbrücken UR - http://scidok.sulb.uni-saarland.de/volltexte/2011/3659 ER -