Please use this identifier to cite or link to this item: doi:10.22028/D291-41886
Title: Endoscopic-Assisted Microsurgical Meningioma Resection in the Skull Base via Minicraniotomy: Is There a Difference in Radicality and Outcome between Anterior Skull Base and Posterior Fossa?
Author(s): Kanczok, Thomas
Fischer, Gerrit
Senger, Sebastian
Linsler, Stefan
Language: English
Title: Cancers
Volume: 16
Issue: 7
Publisher/Platform: MDPI
Year of Publication: 2024
Free key words: meningioma
endoscopic assisted
skull base
radicality
neuroendoscopy
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: Keyhole-based approaches are being explored for skull base tumor surgery; aiming for reduced complications while maintaining resection success rates. This study evaluates skull base meningiomas resected using an endoscopic-assisted microsurgical keyhole approach, comparing outcomes with standard procedures. Methods: Between 2013 and 2019; 71 out of 89 patients were treated using an endoscopic-assisted microsurgical procedure. A total of 42 meningiomas were localized at the anterior skull base and 29 in the posterior fossa. The surgical techniques and use of an endoscope were analyzed and compared in terms of complications, surgical radicality, outcome, and recurrences in the patients’ follow-up. Results: The two different cohorts yielded similar rates of GTR (anterior skull base: 80% versus posterior fossa: 82%). The complication rate was 31% for the posterior fossa and 16% for the anterior skull base. An endoscope was used in 79% of all cases. Tumor remnants were detected by means of endoscopic visualization in 58.6% of posterior fossa and 33% of anterior skull base meningiomas. The statistical analysis revealed significantly higher benefits from endoscope use in the posterior fossa cohort (p < 0.05). Conclusions: The results revealed that endoscopy was beneficial in both locations. The identification of remnant tumor tissue and the benefit of endoscopy were clearly higher in the posterior fossa. Endoscopic assistance is a very helpful tool for increasing radicality, providing a better anatomical overview during surgery, and better identifying remnant tumor tissue in skull base meningioma surgery.
DOI of the first publication: 10.3390/cancers16071391
URL of the first publication: https://doi.org/10.3390/cancers16071391
Link to this record: urn:nbn:de:bsz:291--ds-418864
hdl:20.500.11880/37559
http://dx.doi.org/10.22028/D291-41886
ISSN: 2072-6694
Date of registration: 29-Apr-2024
Description of the related object: Supplementary Materials
Related object: https://www.mdpi.com/article/10.3390/cancers16071391/s1
Faculty: M - Medizinische Fakultät
Department: M - Neurochirurgie
Professorship: M - Keiner Professur zugeordnet
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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