Please use this identifier to cite or link to this item:
doi:10.22028/D291-42017
Title: | Descemet's membrane endothelial keratoplasty is the predominant keratoplasty procedure in Germany since 2016: a report of the DOG-section cornea and its keratoplasty registry |
Author(s): | Flockerzi, Elias Turner, Christina Seitz, Berthold |
Language: | English |
Title: | The British Journal of Ophthalmology |
Publisher/Platform: | BMJ |
Year of Publication: | 2023 |
DDC notations: | 610 Medicine and health |
Publikation type: | Journal Article |
Abstract: | Background/aims This retrospective multicentric panel study provides absolute numbers, types of and indications for corneal transplantation in Germany from 2011 to 2021 and sets them into the international context. Methods A questionnaire was sent to the 104 German ophthalmologic surgery departments and 93 (89%) provided their data. Results The number of reported keratoplasties more than doubled from 2011 (n=4474) to 2021 (n=8998). Lamellar keratoplasties (49% posterior (n=2883), 4% anterior (n=231)) surpassed penetrating keratoplasty (PKP, 47%, n=2721) for the first time in 2014. Since 2016, Descemet’s membrane endothelial keratoplasty (DMEK) has become the predominant keratoplasty procedure in Germany. Its number increased by 1.5-fold from 3850 (2016) to 5812 (2021). Main indications in 2021 were Fuchs’ endothelial corneal dystrophy (FECD, 43%), pseudophakic corneal decompensation (12%), repeated keratoplasty (11%), infections (7%), keratoconus (6%) and corneal scarring (4%, others: 9%). The PKP percentage decreased from 70.2% in 2011 (n=3141) to 31.7% in 2021 (n=2853). Descemet’s stripping (automated) endothelial keratoplasties (DSAEKs) decreased to 1% in 2021 (n=74). 98.6% of all posterior lamellar keratoplasties were DMEKs in Germany in 2021. The number of deep anterior lamellar keratoplasties (DALKs) remained comparable from 2011 (n=269) to 2021 (n=251, 2.8%). Conclusion Main indications for corneal transplantation in Germany (2021) were FECD and pseudophakic corneal decompensation. DMEK is by far the predominant corneal transplantation procedure since 2016 followed by PKP, whose absolute number decreased only slightly during the decade from 2011 to 2021. DALK proportions remain low, but stable, whereas DSAEK decreased annually and plays a minor role in Germany. Trial registration number NCT03381794. |
DOI of the first publication: | 10.1136/bjo-2022-323162 |
URL of the first publication: | https://doi.org/10.1136/bjo-2022-323162 |
Link to this record: | urn:nbn:de:bsz:291--ds-420173 hdl:20.500.11880/37593 http://dx.doi.org/10.22028/D291-42017 |
ISSN: | 1468-2079 0007-1161 |
Date of registration: | 7-May-2024 |
Faculty: | M - Medizinische Fakultät |
Department: | M - Augenheilkunde |
Professorship: | M - Prof. Dr. Berthold Seitz |
Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
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bjo-2022-323162.full.pdf | 1,11 MB | Adobe PDF | View/Open |
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