Please use this identifier to cite or link to this item:
doi:10.22028/D291-42166
Title: | Impact of uncertainties in biometric parameters on intraocular lens power formula predicted refraction using a Monte-Carlo simulation |
Author(s): | Langenbucher, Achim Hoffmann, Peter Cayless, Alan Bolz, Matthias Wendelstein, Jascha Szentmáry, Nóra |
Language: | English |
Title: | Acta Ophthalmologica |
Volume: | 102 (2024) |
Issue: | 3 |
Pages: | e285-e295 |
Publisher/Platform: | Wiley |
Year of Publication: | 2023 |
Free key words: | biometric measures error propagation IOL formula predicted refractive outcome ISO labelling tolerances Monte–Carlo simulation within-subject standard deviation |
DDC notations: | 610 Medicine and health |
Publikation type: | Journal Article |
Abstract: | Purpose: The purpose of this study was to investigate the uncertainty in the formula predicted refractive outcome REFU after cataract surgery resulting from measurement uncertainties in modern optical biometers using literature data for within-subject standard deviation Sw. Methods: This Monte–Carlo simulation study used a large dataset containing 16 667 preoperative IOLMaster 700 biometric measurements. Based on literature Sw values, REFU was derived for both the Haigis and Castrop formulae using error propagation strategies. Using the Hoya Vivinex lens (IOL) as an example, REFU was calculated both with (WLT) and without (WoLT) consideration of IOL power labelling tolerances. Results: WoLT the median REFU was 0.10/0.12 dpt for the Haigis/Castrop formula, and WLT it was 0.13/0.15 dpt. WoLT REFU increased systematically for short eyes (or high power IOLs), and WLT this effect was even more pronounced because of increased labelling tolerances. WoLT the uncertainty in the measurement of the corneal front surface radius showed the largest contribution to REFU, especially in long eyes (and low power IOLs). WLT the IOL power uncertainty dominated in short eyes (or high power IOLs) and the uncertainty of the corneal front surface in long eyes (or low power IOLs). Conclusions: Compared with published data on the formula prediction error of refractive outcome after cataract surgery, the uncertainty of biometric measures seems to contribute with ⅓ to ½ to the entire standard deviation. REFU systematically increases with IOL power and decreases with axial length. |
DOI of the first publication: | 10.1111/aos.15726 |
URL of the first publication: | https://onlinelibrary.wiley.com/doi/full/10.1111/aos.15726 |
Link to this record: | urn:nbn:de:bsz:291--ds-421660 hdl:20.500.11880/37844 http://dx.doi.org/10.22028/D291-42166 |
ISSN: | 1755-3768 1755-375X |
Date of registration: | 11-Jun-2024 |
Faculty: | M - Medizinische Fakultät |
Department: | M - Augenheilkunde |
Professorship: | M - Univ.-Prof. Dr. Dipl.-Ing. Achim Langenbucher M - Prof. Dr. med. Nóra Szentmáry |
Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
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File | Description | Size | Format | |
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Acta Ophthalmologica - 2023 - Langenbucher - Impact of uncertainties in biometric parameters on intraocular lens power.pdf | 3,29 MB | Adobe PDF | View/Open |
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