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doi:10.22028/D291-43390 | Title: | Diagnostic value of isolated plasma biomarkers and its combination in neurodegenerative dementias: A multicenter cohort study |
| Author(s): | Chen, Guangyi Wang, Yunyun Tao, Qingqing Lu, Peilin Meng, Fanxia Zhuang, Liying Qiao, Song Zhang, Ying Luo, Benyan Liu, Yang Peng, Guoping |
| Language: | English |
| Title: | Clinica chimica acta : international journal of clinical chemistry and applied molecular biology |
| Volume: | 558 |
| Publisher/Platform: | Elsevier |
| Year of Publication: | 2024 |
| Free key words: | Alzheimer’s disease Frontotemporal dementia Progressive supranuclear palsy Combination Diagnostic accuracy |
| DDC notations: | 620 Engineering and machine engineering |
| Publikation type: | Journal Article |
| Abstract: | Plasma amyloid-β (Aβ), phosphorylated tau-181 (p-tau181), neurofilament light (NfL) and glial fibrillary acidic protein (GFAP) potentially aid in the diagnosis of neurodegenerative dementias. We aim to conduct a comprehensive comparison between different biomarkers and their combination, which is lacking, in a multicenter Chinese dementia cohort consisting of Alzheimer's disease (AD), frontotemporal dementia (FTD), and progressive supranuclear palsy (PSP). |
| DOI of the first publication: | 10.1016/j.cca.2024.118784 |
| URL of the first publication: | https://www.sciencedirect.com/science/article/pii/S0009898124010258 |
| Link to this record: | urn:nbn:de:bsz:291--ds-433904 hdl:20.500.11880/38913 http://dx.doi.org/10.22028/D291-43390 |
| ISSN: | 1873-3492 0009-8981 |
| Date of registration: | 7-Nov-2024 |
| Faculty: | NT - Naturwissenschaftlich- Technische Fakultät |
| Department: | NT - Materialwissenschaft und Werkstofftechnik |
| Professorship: | NT - Prof. Dr. Volker Presser |
| Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
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|---|---|---|---|---|
| 1-s2.0-S0009898124010258-main.pdf | 1,92 MB | Adobe PDF | View/Open |
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